Synthesis of defective MOF-801 via an environmentally benign approach for diclofenac removal from water streams

  • chair:

    Prasetya, N. / Li, K. (2022)

  • place:

    Separation and Purification Technology, 2022,  301, 122024

  • Date: August 2022
  • Abstract

    Diclofenac is one of the most popular non-steroidal anti-inflammatory drugs (NSAIDs) which has been widely
    used worldwide. Despite its popularity, its accumulation in the environment poses danger to the aquatic lives and
    its removal from the environment is paramount important. Although some conventional adsorbents such as
    activated carbon can be readily used to address this issue, they usually suffer from low diclofenac adsorption
    capacity (around 200 mg g 1), resulting in bulky adsorption systems. To overcome this problem, high perfor-
    mance materials such as metal organic frameworks (MOFs) can be employed. Here, we report that we syn-
    thesised defective MOF-801 for enhanced diclofenac adsorption via a simple and environmentally benign
    approach. Differing from a conventional MOF synthesis that usually requires the use of organic solvents at high
    temperature, the defective MOF-801 could be synthesised at room temperature and by changing the reaction
    medium from dimethylformamide to water. In addition, we have also successfully shown in this study that the
    defect concentration in MOF-801 can be rationally tuned by adjusting the modulator concentration (formic acid)
    in the synthesis solution. The resulting defective MOF-801 can then be used for environmental remediation,
    which we have shown here by employing them as an adsorbent for diclofenac removal from water streams. The
    enhanced adsorption of defective MOF-801 in comparison to its non-defective counterpart is due to the pore
    enlargement of the defective MOF-801 which provides a better pathway to access the adsorption sites. The
    maximum diclofenac adsorption capacity in a highly defective MOF-801 can reach as high as 680 mg g 1, which
    is almost 4 times higher than its non-defective counterpart. This study then opens possibilities to engineer the
    MOF particles for environmental remediation.