Hemolysis Pathways during Storage of Erythrocytes and Inter-Donor Variability in Erythrocyte Morphology
Melzak, K.A. / Spouge J.L. / Boecker C. / Kirschhöfer F. / Brenner-Weiss G. / Bieback K. (2020)
Transfus Med Hemother, 2020, doi.org/10.1159/000508711
- Date: Juli 2020
Background: Red blood cells (RBCs) stored for transfusions can lyse over the course of the storage period. The lysis is traditionally assumed to occur via the formation of spicu-lated echinocyte forms, so that cells that appear smoother are assumed to have better storage quality. We investigate this hypothesis by comparing the morphological distribu-tion to the hemolysis for samples from different donors.