Institute of Functional Interfaces

Hemolysis Pathways during Storage of Erythrocytes and Inter-Donor Variability in Erythrocyte Morphology

  • chair:

    Melzak, K.A. / Spouge J.L. /  Boecker C. / Kirschhöfer F. / Brenner-Weiss G. / Bieback K. (2020)

  • place:

    Transfus Med Hemother, 2020, doi.org/10.1159/000508711

  • Date: Juli 2020
  • Abstract

    Background: Red blood cells (RBCs) stored for transfusions can lyse over the course of the storage period. The lysis is traditionally assumed to occur via the formation of spicu-lated echinocyte forms, so that cells that appear smoother are assumed to have better storage quality. We investigate this hypothesis by comparing the morphological distribu-tion to the hemolysis for samples from different donors.