The corresponding anisotropic coefficients of thermal expansion (CTE) amount to (−75 ± 16) × 10−6 K−1 in the direction perpendicular to the substrate and to (11.7 ± 3.7) × 10−6 K−1 in the direction parallel to the substrate surface. These values substantially differ from the intrinsic CTE, measured for powder MOFs (−4.1 × 10−6 K−1). The substrate-induced anisotropic thermal expansion allows for a direct measurement of the Poisson's ratio of MOF materials, which is hardly measurable for powder MOFs. The Poisson's ratio of HKUST-1 was determined to be 0.69 ± 0.37. Furthermore, thermal cycling experiments of the HKUST-1 SURMOFs reveal a pronounced stability, a necessary requirement for using MOFs in thermal response sensor devices and for high-temperature membrane separation.