O3/UV/H2O2 advanced oxidation process (AOP) was employed to degrade antibiotic berberine hydrochloride (BH) in pharmaceutical wastewater. The effects of initial solution pH, H2O2 dosage and O3 dosage on the berberine hydrochloride removal performance were investigated with synthetic wastewater.
The optimum conditions of initial pH value of 7.0, H2O2 dosage of 3.0 mM, O3 dosage of 10.3 mg/min and the reaction time of 45 min were determined and the removal efficiency of berberine hydrochloride (C 0 = 1500 mg/L) reached 94.1 %. A small amount addition of H2O2 to O3/UV system greatly improved the berberine hydrochloride removal efficiency.
The variations of pH value, ammonium nitrogen and conductivity were analyzed to confirm the degradation of BH. Under the optimal experimental conditions, O3/UV/H2O2 was used to treat the actual berberine hydrochloride wastewater. It demonstrated that the biodegradability of berberine hydrochloride wastewater was obviously promoted and the ratio of biochemical oxygen demand (BOD5) to chemical oxygen demand (COD) was improved from 0.02 up to 0.29, 15 times greater than that of original wastewater.
The costs of four O3-based advanced oxidation processes, O3, O3/UV, O3/H2O2 and O3/UV/H2O2, were also calculated and compared, indicating that O3/UV/H2O2 was the best choice taking into account both the cost and the efficiency. It suggested that the O3/UV/H2O2 advanced oxidation process could not only remove berberine hydrochloride more efficiently but also reduce the costs significantly.